E319

E319

SCHEMBL26745

CC(C)(C)c1cc(O)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
ALOX15 P16050 5/20 1.00
LMNA P02545 3/20 1.00
HSD17B10 Q99714 2/20 1.00
TYR P14679 2/20 1.00
NR1I2 O75469 1/20 1.00
CYP2C9 P11712 1/20 1.00
MIF P14174 1/20 1.00
HTT P42858 1/20 1.00
NFE2L2 Q16236 1/20 1.00
GAA P10253 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.59
KDM4E B2RXH2 1/20 0.59
CYP1A2 P05177 1/20 0.59
MAPT P10636 1/20 0.59
ATP2A2 P16615 1/20 0.59
ATP2A3 Q93084 1/20 0.59
TDP1 Q9NUW8 3/20 0.52
TSHR P16473 2/20 0.52
ESR1 P03372 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E319 SCHEMBL27469266 1.00 ALDH1A1 (1.00) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL29350903 1.00 ALDH1A1 (1.00) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL26929486 0.98 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL10908851 0.98 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL28120000 0.98 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL10908842 0.98 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL18941443 0.98 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL18940889 0.98 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL28293722 0.98 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL10625736 0.98 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 41993 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144813-A1 SOLUBLE FIBER COMPOSITIONS TO PREVENT FATTY LIVER AND ALZHEIMER'S CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITÉCNICO NACIONAL (MX) 2026-05-28 US claimed
EP-4747325-A1 LOW GWP COMPOSITIONS COMPRISING HFO-1252ZC AND USES THEREOF The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747323-A1 BLEND COMPOSITIONS CONTAINING DIFLUOROPROPENE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747327-A1 METHODS AND APPARATUS USING DIFLUOROPROPENE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747328-A1 COMPOSITIONS COMPRISING DIFLUOROPROPENE AND USES THEREOF The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
CN-122095147-A Leather treatment agent for imparting water and oil repellency comprising a silicone- (meth) acrylate copolymer and an organic binder 2026-05-26 CN claimed
CN-122077251-A Lead-free halogen-free soldering paste for QFN device and preparation method thereof 2026-05-26 CN claimed
US-12638399-B2 Method for determining total aldehydes in one or more of crude 2,5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA) and esters of these ARCHER-DANIELS-MIDLAND COMPANY (US) 2026-05-26 US claimed
CN-121537325-B Method for separating and purifying retinol from fermentation liquor and application thereof Hangzhou Xinhai enzyme source Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12635720-B2 Prepared foods having high efficacy omega-6/omega-3 balanced polyunsaturated fatty acids OMEGA FOODS LLC (US) 2026-05-26 US claimed
US-4135033-A HEAT DISSOCIABLE MOLECULAR COMPLEX BARRIER LAYER LAWTON WILLIAM R 1979-01-16 US claimed
US-4127564-A DIOLEFIN-PHENOLIC COPOLYMER DYNAPOL (US) 1978-11-28 US claimed
US-4115370-A CROSSLINKING WITH VINYL MONOMERS SNIA VISCOSA SOCIETA' NAZIONALE INDUSTRIA APPLICAZIONI VISCOSA S.P.A. (IT) 1978-09-19 US claimed
US-4105451-A 2-MERCAPTO-BENZOTHIAZOLE, -BENZOXAZOLE, -BENZIMIDAZOLE OR -BENZOSELENAZOLE; HETEROCYCLIC THIONE SILVER SALT; REDUCING AGENT; BINDER; SILVER HALIDE AND SENSITIZER EASTMAN KODAK COMPANY (US) 1978-08-08 US claimed
US-4101398-A Process for hardening a resin which is the reaction product of an epoxy resin, an olefinically unsaturated monocarboxylic acid and a polycarboxylic acid anhydride unit HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US claimed
US-4083890-A Unsaturated ester resin/monomer blend with hydroperoxide, vanadium compound and ketone peroxide for controlled gel time THE DOW CHEMICAL COMPANY (US) 1978-04-11 US claimed
US-3997705-A Method of coagulating a fluoro-elastomer from an aqueous dispersion thereof DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-12-14 US claimed
US-3997346-A Method for stabilizing the image of a thermally developable photosensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US claimed
US-3996199-A Oil soluble polymeric antioxidant prepared by condensation of divinylbenzene, hydroxyanisole, tertiary butyl hydroquinone, tertiary butyl phenol and bisphenol A under ortho alkylation conditions DYNAPOL CORPORATION (US) 1976-12-07 US claimed
US-3979412-A Process for producing 3-anilino-5-pyrazolones FUJI PHOTO FILM CO., LTD. (JA) 1976-09-07 US claimed