SCHEMBL26745801

SCHEMBL26745801

Fc1ccc2nc(-c3sc(-c4nc5cc6cc7oc(-c8sc(-c9nc%10ccc(F)cc%10s9)c(F)c8F)nc7cc6cc5o4)c(F)c3F)sc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 12/20 0.44
▸ GFER P55789 2/20 0.40
▸ AXL P30530 1/20 0.40
▸ ILK Q13418 2/20 0.40
▸ SULT1A1 P50225 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ MAOB P27338 1/20 0.38
▸ F2RL3 Q96RI0 1/20 0.38
▸ CCNE1 P24864 1/20 0.38
▸ CDK2 P24941 1/20 0.38
▸ CDK5 Q00535 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26745806 0.90 AHR (0.40) APPILKF2RL3
SCHEMBL26745798 0.83 APP (0.42) APPGFERAXLILKSULT1A1
SCHEMBL26745404 0.83 APP (0.54) APPGFERAXLILKSULT1A1
SCHEMBL26745763 0.81 APP (0.45) APPGFERAXLILKSULT1A1
SCHEMBL26745790 0.79 APP (0.42) APPGFERAXLILKSULT1A1
SCHEMBL26746068 0.75 APP (0.39) APPGFERAXLILKSULT1A1
SCHEMBL26745405 0.74 AHR (0.48) APPGFERAXLILKSULT1A1
SCHEMBL26745810 0.74 AHR (0.39) APPILKF2RL3
SCHEMBL26745779 0.72 AHR (0.41) APPILKKDM4EALDH1A1MAPT
SCHEMBL26745378 0.67 APP (0.55) APPGFERAXLILKSULT1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345826-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-10-26 — — US disclosed
US-20230345826-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345826-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND TEAD1, CRY1, CPNE4 APP 1687/4885GFER 3092/4885AXL 4152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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