⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4136354 | 0.61 | — | — | |
| SCHEMBL6392835 | 0.55 | — | — | |
| SCHEMBL18285 | 0.55 | — | — | |
| SCHEMBL35997 | 0.55 | — | — | |
| SCHEMBL8380791 | 0.55 | — | — | |
| SCHEMBL724735 | 0.55 | — | — | |
| SCHEMBL23089736 | 0.50 | — | — | |
| SCHEMBL23458664 | 0.50 | — | — | |
| SCHEMBL23458655 | 0.50 | — | — | |
| Bromide SCHEMBL22773716 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1024 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409505-B | Preparation method of posaconazole intermediate | 山东金城医药研究院有限公司 | 2023-10-17 | — | — | CN | claimed |
| US-11629152-B2 | Compound with anticancer activity | KYOWA KIRIN CO., LTD. (JP) | 2023-04-18 | — | — | US | claimed |
| US-11591344-B2 | — | — | 2023-02-28 | — | — | US | claimed |
| CN-115677810-A | Double-stranded oligonucleotide, composition containing double-stranded oligonucleotide, conjugate, preparation method and application | 苏州瑞博生物技术股份有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-114957053-A | Oxoethylene compound or pharmaceutically acceptable salt thereof, preparation method and application thereof, pharmaceutical composition and application thereof | 中国医学科学院医药生物技术研究所 | 2022-08-30 | — | — | CN | claimed |
| CN-110305072-A | Compound and its application with phosphodiesterase 4 D and acid sphingomyelinase inhibitory activity | 中国药科大学 | 2019-10-08 | — | — | CN | claimed |
| CN-105814049-B | Fused tricyclic imdazole derivatives as TNF active regulator | UCB生物制药私人有限公司 | 2019-03-12 | — | — | CN | claimed |
| CN-105814047-B | Fused tricyclic imdazole derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-10-19 | — | — | CN | claimed |
| CN-107793450-A | It is a kind of（Formyl methylene）The preparation method of triphenyl Zheng Phosphonium | 合肥利夫生物科技有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107787319-A | Indazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2018-03-09 | — | — | CN | claimed |
| EP-0377321-A2 | Photopolymerizable composition | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-11 | — | — | EP | claimed |
| EP-0253711-B1 | 1H,3H-pyrrolo[1,2-c]thiazole derivatives, their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1990-05-23 | — | — | EP | claimed |
| EP-0319412-A1 | 2-Piperazinyl-2-oxo-ethylene-substituted flavonoid derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1989-06-07 | — | — | EP | claimed |
| EP-0309043-A2 | Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-03-29 | — | — | EP | claimed |
| US-4783472-A | 1H,3H-pyrrol[1,2-c]thiazole derivatives and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1988-11-08 | — | — | US | claimed |
| EP-0253711-A1 | 1H,3H-pyrrolo[1,2-c]thiazole derivatives, their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1988-01-20 | — | — | EP | claimed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | claimed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | claimed |
| EP-0024931-A2 | 1,2,4-Benzotriazinylaminophenoxyalkane carboxylic acid derivatives, processes for their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-03-11 | — | — | EP | claimed |
| US-4215139-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1980-07-29 | — | — | US | claimed |