Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709939 | 1.00 | SCN4A (0.45) | SCN4ADPP4F2GBA1CYP2C19 | |
| SCHEMBL11252039 | 0.83 | ANPEP (0.42) | — | |
| SCHEMBL9669874 | 0.78 | SCN4A (0.47) | SCN4ADPP4F2GBA1 | |
| SCHEMBL27966124 | 0.78 | DPP4 (0.41) | DPP4 | |
| SCHEMBL27966039 | 0.78 | ADRB2 (0.45) | SCN4ACYP2C19CYP2D6 | |
| SCHEMBL68782 | 0.78 | HTR2A (0.46) | DPP4F2CYP2C19GRIN1GRIN2A | |
| SCHEMBL266309 | 0.77 | SCN4A (0.45) | SCN4ADPP4F2TAAR1 | |
| SCHEMBL7406881 | 0.77 | CYP2C19 (0.57) | SCN4ADPP4F2CYP2C19GRIN2D | |
| SCHEMBL22705600 | 0.77 | SCN4A (0.45) | SCN4ADPP4F2GBA1GRIN2D | |
| SCHEMBL898390 | 0.77 | CYP2C19 (0.57) | SCN4ADPP4F2CYP2C19GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102453001-A | Thiomorpholine compound and preparation method and application thereof | INST MATERIA MEDICA CAMS | 2012-05-16 | — | — | CN | claimed |
| EP-1144384-B1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2007-10-31 | — | — | EP | claimed |
| CN-117327244-A | Self-sensitization type radiochromic polyurethane elastomer and preparation method thereof | 四川大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-113549070-B | Preparation method of malavisuo and derivatives thereof | 中国科学院福建物质结构研究所 | 2022-12-06 | — | — | CN | disclosed |
| CN-113549070-A | Preparation method of malavisuo and derivatives thereof | 中国科学院福建物质结构研究所 | 2021-10-26 | — | — | CN | disclosed |
| CN-109476605-A | Benzo-N- hydroxyamide compounds with anti-tumor activity | 意大发马克股份公司 | 2019-03-15 | — | — | CN | disclosed |
| US-20170342451-A1 | BIOSYNTHESIS OF PACLITAXEL INTERMEDIATE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2017-11-30 | — | — | US | disclosed |
| US-9732365-B2 | Biosynthesis of paclitaxel intermediate | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2017-08-15 | — | — | US | disclosed |
| CN-103725725-B | The non-cells,primordial suspension culture of seed of Hainan Plumyew is utilized to produce the method for taxol and precursor baccatin III thereof | TROPICAL CROPS GENETIC RESOURCES INSTITUTE OF CHINESE ACADEMY OF TROPICAL AGRICULTURAL SCIENCES (CN) | 2016-04-20 | — | — | CN | disclosed |
| US-20150284751-A1 | BIOSYNTHESIS OF PACLITAXEL INTERMEDIATE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2015-10-08 | — | — | US | disclosed |
| US-8962889-B2 | Process for producing optically active β-amino aldehyde compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-02-24 | — | — | US | disclosed |
| US-4308380-A | 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4304718-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4203897-A | Penam derivatives | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-05-20 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |
| US-4113940-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
| US-4091210-A | Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-05-23 | — | — | US | disclosed |
| US-4084049-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-3984397-A | CYCLIZATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-10-05 | — | — | US | disclosed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | disclosed |