Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26762044 | 0.97 | AR (0.51) | ARALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL26767388 | 0.90 | AR (0.52) | ARALDH1A1KDM4ETDP1POLB | |
| SCHEMBL26762172 | 0.90 | AR (0.51) | ARALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL26760975 | 0.87 | AR (0.45) | ARALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL26762242 | 0.86 | AR (0.52) | ARALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL26762390 | 0.86 | AR (0.55) | ARALDH1A1KDM4ETDP1POLB | |
| SCHEMBL26749535 | 0.80 | AR (0.61) | ARALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL26750635 | 0.79 | AR (0.60) | ARALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL26750022 | 0.79 | AR (0.60) | ARALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL26762564 | 0.78 | AR (0.56) | ARALDH1A1GAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442942-B1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2023-11-15 | — | — | EP | disclosed |