Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26762242 | 0.89 | AR (0.52) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL19482510 | 0.89 | AR (0.62) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL19482513 | 0.89 | AR (0.62) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL19482516 | 0.89 | AR (0.62) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL19482511 | 0.89 | AR (0.62) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL19482512 | 0.89 | AR (0.62) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL26762390 | 0.89 | AR (0.55) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL26761198 | 0.88 | AR (0.56) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL19459775 | 0.87 | AR (0.62) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL19460290 | 0.87 | AR (0.62) | ARHTTHIF1AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442942-B1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2023-11-15 | — | — | EP | disclosed |