Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24083864 | 0.90 | AR (0.67) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL26761242 | 0.90 | AR (0.51) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL24083794 | 0.89 | AR (0.55) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL26762564 | 0.88 | AR (0.56) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL19482529 | 0.87 | AR (0.63) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL19482530 | 0.87 | AR (0.63) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL19482532 | 0.87 | AR (0.63) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL19482531 | 0.87 | AR (0.63) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL19482533 | 0.87 | AR (0.63) | ARHTTHIF1AALDH1A1KCNH2 | |
| SCHEMBL19459860 | 0.85 | AR (0.56) | ARHTTHIF1AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442942-B1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2023-11-15 | — | — | EP | disclosed |