SCHEMBL26762581

SCHEMBL26762581

Cc1cc(-n2nc3c(c2-n2cc[nH]c2=O)[C@H](F)N(C(=O)OC(C)(C)C)CC3)cc(C)c1Cl

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 4/20 0.31
▸ C5AR1 P21730 1/20 0.31
▸ TP53 P04637 1/20 0.30
▸ CRHR1 P34998 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20014828 0.91 GLP1R (0.33) GLP1RC5AR1
SCHEMBL26122776 0.84 GLP1R (0.36) GLP1R
SCHEMBL20014787 0.84 GLP1R (0.36) GLP1R
SCHEMBL21183679 0.83 GLP1R (0.36) GLP1R
SCHEMBL38651890 0.81 GLP1R (0.35) GLP1R
SCHEMBL20014993 0.81 C5AR1 (0.41) GLP1RC5AR1TP53
SCHEMBL20014818 0.81 GLP1R (0.31) GLP1R
SCHEMBL21175150 0.80 GLP1R (0.35) GLP1RCRHR1
SCHEMBL38652284 0.80 GLP1R (0.35) GLP1R
SCHEMBL31692385 0.80 GLP1R (0.34) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382912-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-11-30 — — US disclosed
US-11814381-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382912-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, GPR119, GIPR GLP1R 1/4885C5AR1 3777/4885TP53 4060/4885
US-11814381-B2 Pyrazolopyridine derivative having GLP-1 receptor agonist effect GLP1R, GPR119, GIPR GLP1R 1/4885C5AR1 3728/4885TP53 4750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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