⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16907336 | 1.00 | — | — | |
| SCHEMBL1170855 | 0.84 | — | — | |
| SCHEMBL1170387 | 0.82 | CA1 (0.45) | — | |
| SCHEMBL1117346 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL1117350 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL1117304 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL1117394 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL1117308 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL1117311 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL17807542 | 0.80 | TSHR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676702-B2 | Methods for synthesizing amatoxin building block and amatoxins | HEIDELBERG PHARMA GMBH (DE) | 2017-06-13 | — | — | US | claimed |
| US-9630907-B2 | — | — | 2017-04-25 | — | — | US | claimed |
| EP-2872479-B1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | HEIDELBERG PHARMA GMBH (DE) | 2016-06-08 | — | — | EP | claimed |
| US-20150210628-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | HEIDELBERG PHARMA GMBH (DE) | 2015-07-30 | — | — | US | claimed |
| EP-2872479-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | Heidelberg Pharma GmbH (DE) | 2015-05-20 | — | — | EP | claimed |
| WO-2014009025-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | HEIDELBERG PHARMA GMBH (DE) | 2014-01-16 | — | — | WO | claimed |
| EP-2684865-A1 | Methods for synthesizing amatoxin building block and amatoxins | Heidelberg Pharma GmbH (DE) | 2014-01-15 | — | — | EP | claimed |
| CN-1078590-C | Process for preparing 2-oxindoles and N-hydroxy-2-oxindoles | CATALYTICA INC (US) | 2002-01-30 | — | — | CN | claimed |
| CN-1177347-A | Process for preparing 2 -oxindoles and N -hydroxy -2 -oxindoles | CATALYTICA INC (US) | 1998-03-25 | — | — | CN | claimed |
| US-5604294-A | IMMUNOSUPRESSIVE, ANTIMICROBIAL, ANTIFUNGAL, ANTIVIRAL, ANTI-INFLAMMATORY AND ANTIPROLIFERATIVE ACTIVITY | ABBOTT LABORATORIES | 1997-02-18 | — | — | US | claimed |
| WO-1994021635-A1 | MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | claimed |
| US-4861925-A | Process for the preparation of nitroolefins | W. R. GRACE & CO.-CONN. (US) | 1989-08-29 | — | — | US | claimed |
| US-4287291-A | SATURATED ALIPHATIC OR ALICYCLIC ALCOHOL IN PROCESSING SOLUTION | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-09-01 | — | — | US | claimed |
| CN-114585628-B | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-112479890-B | Preparation method of nitro compound | 苏州亚科科技股份有限公司 | 2023-09-26 | — | — | CN | disclosed |
| US-11542277-B2 | Nitrated hydrocarbons, derivatives, and processes for their manufacture | ANGUS CHEMICAL COMPANY (US) | 2023-01-03 | — | — | US | disclosed |
| US-4009030-A | DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3998637-A | SULFONAMIDO COMPOUND OR HYDROQUINONE DERIVATIVE | EASTMAN KODAK COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
| US-3947584-A | Novel indolyl alkyl amines, method of producing same, and their use as anorectic agents | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1976-03-30 | — | — | US | disclosed |
| US-3930864-A | AUXILIARY MORDANT LAYER FOR EXCESS DYE FORMED IN INTEGRAL COLOR TRANSFER ASSEMBLAGE | EASTMAN KODAK COMPANY (US) | 1976-01-06 | — | — | US | disclosed |