Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 4/20 | 0.59 |
| ▸ | PKLR | P30613 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26770701 | 0.95 | PDE2A (0.61) | PRKDCPKLRNPSR1RXFP1PDE2A | |
| SCHEMBL26766718 | 0.83 | PDE2A (0.63) | PRKDCPKLRNPSR1RXFP1PDE2A | |
| SCHEMBL26770796 | 0.82 | PDE2A (0.61) | PRKDCPKLRNPSR1RXFP1PDE2A | |
| SCHEMBL26766723 | 0.81 | CCR4 (0.64) | PKLRNPSR1RXFP1PDE2ACCR4 | |
| SCHEMBL16663940 | 0.78 | PDE2A (0.85) | PKLRNPSR1RXFP1PDE2AHSD17B3 | |
| SCHEMBL1938064 | 0.74 | SLC16A3 (0.51) | PRKDCSLC16A3MAPTKDM4EALDH1A1 | |
| SCHEMBL31061328 | 0.74 | PRKDC (1.00) | PRKDC | |
| SCHEMBL3533604 | 0.74 | PRKDC (1.00) | PRKDC | |
| SCHEMBL28499055 | 0.74 | PRKDC (0.68) | PRKDCHSD17B3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5440694 | 0.73 | PRKDC (0.55) | PRKDCMAPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820751-B2 | Urolithin derivatives and methods of use thereof | VANDRIA SA (CH) | 2023-11-21 | — | — | US | disclosed |
| US-11820751-B2 | Urolithin derivatives and methods of use thereof | VANDRIA SA (CH) | 2023-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820751-B2 | Urolithin derivatives and methods of use thereof | NLN, UQCRC2, TUFM | PRKDC 2451/4885PKLR 1783/4885NPSR1 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.