Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125953 | 0.81 | CA12 (0.40) | CA12CA1CA2CA9MGAM | |
| SCHEMBL265272 | 0.79 | CA12 (0.43) | CA12CA1CA2CA9MGAM | |
| SCHEMBL17666078 | 0.77 | ALDH1A1 (0.31) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL17666081 | 0.77 | ALDH1A1 (0.31) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL18699228 | 0.76 | CYP3A4 (0.39) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL26779100 | 0.74 | CA12 (0.42) | CA12CA1CA2CA9MGAM | |
| SCHEMBL265222 | 0.73 | CA12 (0.39) | CA12CA1CA2CA9MGAM | |
| SCHEMBL11029836 | 0.72 | CA12 (0.41) | CA12CA1CA2CA9MGAM | |
| SCHEMBL11265878 | 0.70 | CA12 (0.48) | CA12CA1CA2CA9MGAM | |
| SCHEMBL18796463 | 0.70 | CA12 (0.39) | CA12CA1CA2CA9MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215559-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | ARIA PHARMACEUTICALS, INC. (US) | 2023-11-09 | — | — | WO | disclosed |