Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288077 | 0.89 | EPHX1 (0.51) | EPHX1HRH3RAB9ANPC1DRD4 | |
| SCHEMBL26764376 | 0.89 | EPHX1 (0.51) | EPHX1HRH3RAB9ANPC1DRD4 | |
| SCHEMBL24011382 | 0.83 | EPHX1 (0.64) | EPHX1RAB9ANPC1DRD4HPGD | |
| SCHEMBL24011131 | 0.80 | EPHX1 (0.72) | EPHX1RAB9ANPC1DRD4HPGD | |
| SCHEMBL24011160 | 0.78 | EPHX1 (0.69) | EPHX1RAB9ANPC1DRD4HPGD | |
| SCHEMBL23747606 | 0.78 | CHRM1 (0.53) | EPHX1HRH3RAB9ANPC1HPGD | |
| SCHEMBL26098540 | 0.78 | CHRM1 (0.53) | EPHX1HRH3RAB9ANPC1HPGD | |
| SCHEMBL24011289 | 0.74 | EPHX1 (0.71) | EPHX1RAB9ANPC1DRD4HPGD | |
| SCHEMBL12196171 | 0.74 | EPHX1 (1.00) | EPHX1RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL24011292 | 0.73 | EPHX1 (0.64) | EPHX1RAB9ANPC1DRD4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | EPHX1 3913/4885HRH3 1432/4885RAB9A 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.