Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | PPIG | Q13427 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26764376 | 1.00 | EPHX1 (0.51) | EPHX1HRH3RAB9ANPC1TP53 | |
| SCHEMBL26776849 | 0.89 | EPHX1 (0.57) | EPHX1HRH3RAB9ANPC1TP53 | |
| SCHEMBL26633789 | 0.83 | EPHX1 (0.55) | EPHX1HRH3RAB9ANPC1TP53 | |
| SCHEMBL24011134 | 0.80 | EPHX1 (0.61) | EPHX1RAB9ANPC1TP53DRD4 | |
| SCHEMBL30634137 | 0.79 | EPHX1 (0.51) | EPHX1HRH3RAB9ANPC1TP53 | |
| SCHEMBL30288079 | 0.78 | EPHX1 (0.59) | EPHX1RAB9ANPC1TP53DRD4 | |
| SCHEMBL26098540 | 0.75 | CHRM1 (0.53) | EPHX1HRH3RAB9ANPC1TP53 | |
| SCHEMBL23747606 | 0.75 | CHRM1 (0.53) | EPHX1HRH3RAB9ANPC1TP53 | |
| SCHEMBL24011142 | 0.75 | EPHX1 (0.60) | EPHX1RAB9ANPC1TP53DRD4 | |
| SCHEMBL24011297 | 0.73 | EPHX1 (0.55) | EPHX1RAB9ANPC1TP53DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843295-A | NAMPT modulators | 赛特凯恩蒂克公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-4146640-A2 | NAMPT MODULATORS | Cytokinetics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |