Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635887 | 0.90 | STING1 (0.62) | STING1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL30697680 | 0.90 | STING1 (0.62) | STING1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL26778230 | 0.90 | ALDH1A1 (0.52) | STING1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL26778207 | 0.88 | STING1 (0.60) | STING1PARP10PARP15PARP14MAOB | |
| SCHEMBL23635831 | 0.86 | ALDH1A1 (0.55) | STING1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL23635832 | 0.84 | STING1 (0.55) | STING1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL23635882 | 0.83 | ALDH1A1 (0.52) | STING1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL30313238 | 0.80 | ALDH1A1 (0.59) | STING1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL23635796 | 0.80 | ALDH1A1 (0.59) | STING1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL23630828 | 0.79 | STING1 (0.59) | STING1ALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793988-B1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-11-15 | — | — | EP | disclosed |