Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24974308 | 0.76 | GRIN2D (0.38) | — | |
| SCHEMBL25777879 | 0.75 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL18596002 | 0.74 | CRHBP (0.37) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL22254742 | 0.72 | CRHBP (0.35) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL23077819 | 0.70 | CRHBP (0.34) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL680047 | 0.67 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL25790737 | 0.67 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL24928071 | 0.67 | CRHBP (0.32) | CRHBPCRHR2 | |
| SCHEMBL21690694 | 0.65 | DRD4 (0.31) | — | |
| SCHEMBL25596934 | 0.65 | CRHBP (0.31) | CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348493-A1 | COMPOUND FOR ADJUSTING ACTIVITY OF NMDA RECEPTOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO. LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348493-A1 | COMPOUND FOR ADJUSTING ACTIVITY OF NMDA RECEPTOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | GRIN1, GRIN3A, GRIN2C | CRHBP 1805/4885CRHR2 512/4885ALDH1A1 3847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.