Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 15/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369233 | 1.00 | PDK1 (0.65) | PDK1SMN1; SMN2EPHA2KDRPIK3CD | |
| SCHEMBL23089305 | 0.87 | PDK1 (0.65) | PDK1PIK3CD | |
| SCHEMBL5369230 | 0.85 | PDK1 (0.63) | PDK1PIK3CD | |
| SCHEMBL13204891 | 0.84 | PDK1 (0.47) | PDK1SMN1; SMN2EPHA2KDR | |
| SCHEMBL16750119 | 0.83 | PDK1 (0.60) | PDK1EPHA2KDRPIK3CD | |
| SCHEMBL31224063 | 0.81 | PDK1 (0.58) | PDK1PIK3CD | |
| SCHEMBL8425994 | 0.81 | PDK1 (0.48) | PDK1SMN1; SMN2EPHA2KDR | |
| SCHEMBL11949265 | 0.81 | PDK1 (0.59) | PDK1SMN1; SMN2PIK3CD | |
| SCHEMBL13193522 | 0.80 | PDK1 (0.57) | PDK1SMN1; SMN2EPHA2 | |
| SCHEMBL22732715 | 0.79 | PDK1 (0.47) | PDK1SMN1; SMN2EPHA2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218187-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | UNIVERSITY OF DUNDEE (GB) | 2023-11-16 | — | — | WO | disclosed |