Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15447136 | 0.82 | DPP4 (0.44) | DPP4CYP19A1PADI4FOLH1PSEN1 | |
| SCHEMBL3808952 | 0.80 | DPP4 (0.43) | DPP4CYP19A1PADI4FOLH1PSEN1 | |
| SCHEMBL19935986 | 0.80 | CYP19A1 (0.40) | CYP19A1FOLH1GPR88 | |
| SCHEMBL5334246 | 0.79 | DPP4 (0.43) | DPP4CYP19A1PADI4FOLH1 | |
| SCHEMBL28150959 | 0.78 | DPP4 (0.49) | DPP4CYP19A1PADI4FOLH1PSEN1 | |
| SCHEMBL28150958 | 0.78 | DPP4 (0.49) | DPP4CYP19A1PADI4FOLH1PSEN1 | |
| SCHEMBL13630968 | 0.74 | DPP4 (0.39) | DPP4CYP19A1PADI4FOLH1PSEN1 | |
| SCHEMBL10192257 | 0.74 | FDPS (0.38) | KMT2A | |
| SCHEMBL27348007 | 0.74 | DPP4 (0.39) | DPP4CYP19A1PADI4FOLH1 | |
| SCHEMBL11361006 | 0.73 | CYP19A1 (0.48) | DPP4CYP19A1FOLH1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212019-A1 | PYRIMIDINONE-CONTAINING 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |