Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PREP | P48147 | 4/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19143407 | 0.93 | HPGD (0.47) | HPGDSMN1; SMN2NAMPTGAAKMT2A | |
| SCHEMBL23680948 | 0.93 | HPGD (0.47) | HPGDSMN1; SMN2NAMPTGAAKMT2A | |
| SCHEMBL18731290 | 0.88 | CNR1 (0.43) | HPGDSMN1; SMN2NAMPTGAAKMT2A | |
| SCHEMBL16254979 | 0.83 | CNR1 (0.47) | HPGDSMN1; SMN2GAAKMT2AMAPK1 | |
| SCHEMBL14301360 | 0.80 | HPGD (0.47) | HPGDSMN1; SMN2GAAKMT2AMAPK1 | |
| SCHEMBL1632770 | 0.80 | HPGD (0.47) | HPGDSMN1; SMN2GAAKMT2APREP | |
| SCHEMBL13245892 | 0.80 | HPGD (0.47) | HPGDSMN1; SMN2GAAKMT2AMAPK1 | |
| SCHEMBL13674784 | 0.80 | HPGD (0.47) | HPGDSMN1; SMN2GAAKMT2AMAPK1 | |
| SCHEMBL14218669 | 0.80 | HPGD (0.47) | HPGDSMN1; SMN2GAAKMT2APREP | |
| SCHEMBL1631843 | 0.78 | DPP4 (0.58) | HPGDSMN1; SMN2GAAKMT2APREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220134-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |