Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 10/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | RGS12 | O14924 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 3/20 | 1.00 |
| ▸ | APEX1 | P27695 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678764 | 1.00 | EGFR (1.00) | EGFRERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL29429711 | 1.00 | EGFR (1.00) | EGFRERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL2678762 | 1.00 | EGFR (1.00) | EGFRERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL15075269 | 0.91 | EGFR (0.83) | EGFRERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL6045468 | 0.91 | EGFR (0.83) | EGFRERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL29378337 | 0.90 | EGFR (0.82) | EGFRERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL18292349 | 0.88 | EGFR (1.00) | EGFRERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL31060696 | 0.88 | EGFR (1.00) | EGFRERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL6213665 | 0.84 | EGFR (0.70) | EGFRERBB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL6213656 | 0.84 | EGFR (0.70) | EGFRERBB2KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180340937-A1 | Phosphoinositide (4,5) Bisphosphate as a Diagnostic Tool and Target for Cancer Treatment | JANETOPOULOS CHRISTOPHER (US) | 2018-11-29 | — | — | US | disclosed |
| US-20160266129-A1 | Phosphoinositide (4,5) Bisphosphate as a Diagnostic Tool and Target for Cancer Treatment | JANETOPOULOS CHRISTOPHER (US) | 2016-09-15 | — | — | US | disclosed |
| US-8175860-B2 | Method of inhibiting the growth of Helicobacter pylori | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-05-08 | — | — | US | disclosed |
| US-20100305152-A1 | METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305152-A1 | METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI | HPD, HAAO, HK1 | EGFR 1420/4885ERBB2 704/4885KDM4E 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.