Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634305 | 1.00 | TTR (0.49) | TTRDPP4FDPSCA12CA1 | |
| SCHEMBL26787976 | 0.83 | TTR (0.56) | TTRDPP4FDPSCA12CA1 | |
| SCHEMBL30634265 | 0.83 | TTR (0.56) | TTRDPP4FDPSCA12CA1 | |
| SCHEMBL26634000 | 0.82 | RAB9A (0.50) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL26791034 | 0.81 | TTR (0.53) | TTRDPP4FDPSCA12CA1 | |
| SCHEMBL26791067 | 0.81 | MAOB (0.58) | TTRDPP4FDPSCA12CA1 | |
| SCHEMBL30634286 | 0.81 | MAOB (0.58) | TTRDPP4FDPSCA12CA1 | |
| SCHEMBL30634285 | 0.81 | TTR (0.53) | TTRDPP4FDPSCA12CA1 | |
| SCHEMBL26791168 | 0.81 | TTR (0.52) | TTRDPP4FDPSCA12CA1 | |
| SCHEMBL26634045 | 0.81 | TTR (0.52) | TTRDPP4FDPSCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212565-A2 | MOLECULAR EDITING OF MULTIPLE C-H BONDS BY LEVERAGING RECOGNITION OF DISTANCE, GEOMETRY AND CHIRALITY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-02 | — | — | WO | disclosed |