Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 4/20 | 0.56 |
| ▸ | FABP3 | P05413 | 3/20 | 0.56 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26795524 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 | |
| SCHEMBL26794290 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 | |
| SCHEMBL26794952 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 | |
| SCHEMBL24314079 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 | |
| SCHEMBL26793409 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 | |
| SCHEMBL24314085 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 | |
| SCHEMBL26794950 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 | |
| SCHEMBL24314022 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 | |
| SCHEMBL29532812 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 | |
| SCHEMBL26793283 | 0.87 | FABP7 (0.74) | FABP7FABP3FABP5CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365488-A1 | TRUXILLIC ACID MONOESTER-DERIVATIVES AS SELECTIVE FABP5 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365488-A1 | TRUXILLIC ACID MONOESTER-DERIVATIVES AS SELECTIVE FABP5 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | FABP5, FABP1, FABP4 | FABP7 7/4885FABP3 5/4885FABP5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.