SCHEMBL2679682

SCHEMBL2679682

Cc1c(OC(=O)c2ccccc2)cccc1OC(=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.63
MAPT P10636 3/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
SLC6A3 Q01959 1/20 0.61
POLB P06746 2/20 0.60
ESR1 P03372 4/20 0.59
ESR2 Q92731 4/20 0.59
MEN1 O00255 3/20 0.59
HSD17B10 Q99714 2/20 0.59
JAK2 O60674 1/20 0.59
USP2 O75604 1/20 0.59
GAA P10253 1/20 0.59
ALOX15 P16050 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
LMNA P02545 2/20 0.54
METAP2 P50579 1/20 0.54
METAP1 P53582 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
TOP1 P11387 1/20 0.54
TSHR P16473 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6349146 0.91 POLB (0.73) KMT2AMAPTSMN1; SMN2SLC6A3POLB
SCHEMBL2292938 0.89 ESR1 (0.66) KMT2AMAPTSMN1; SMN2SLC6A3POLB
SCHEMBL28731647 0.88 KMT2A (0.58) KMT2AMAPTSMN1; SMN2SLC6A3POLB
SCHEMBL27717755 0.86 SLC6A3 (0.55) KMT2AMAPTSMN1; SMN2SLC6A3POLB
SCHEMBL725404 0.85 KMT2A (0.76) KMT2AMAPTSMN1; SMN2SLC6A3POLB
SCHEMBL1284160 0.84 KMT2A (0.63) KMT2AMAPTSMN1; SMN2SLC6A3POLB
Acetic Acid SCHEMBL29588064 0.83 KMT2A (0.68) KMT2AMAPTSMN1; SMN2SLC6A3POLB
SCHEMBL16237011 0.83 TOP1 (0.58) KMT2AMAPTSMN1; SMN2SLC6A3POLB
Hydrochloric Acid SCHEMBL16050041 0.83 KMT2A (0.73) KMT2AMAPTSMN1; SMN2SLC6A3POLB
Bromide SCHEMBL29588519 0.83 KMT2A (0.73) KMT2AMAPTSMN1; SMN2SLC6A3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114423811-B Curable composition comprising UV stabilizer 迈图高新材料公司 2024-04-02 CN claimed
CN-114423811-A Curable composition comprising a UV stabilizer 迈图高新材料公司 2022-04-29 CN claimed
US-4478876-A BLEND OF ACRYLATE MONOMER, COLLOIDAL SILICA, ACRYLOXY FUNCTIONAL SILANE, AND PHOTOINITIATORS GENERAL ELECTRIC COMPANY (US) 1984-10-23 US claimed
CN-114423811-B Curable composition comprising UV stabilizer 迈图高新材料公司 2024-04-02 CN disclosed
CN-114423811-A Curable composition comprising a UV stabilizer 迈图高新材料公司 2022-04-29 CN disclosed
CN-102421856-B UV-curable protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG 2014-08-27 CN disclosed
US-8753739-B2 UV-curing protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG (DE) 2014-06-17 US disclosed
CN-101466805-B UV-curable protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG 2013-08-07 CN disclosed
US-20120114933-A1 UV-CURING PROTECTIVE LAYER FOR THERMOPLASTIC SUBSTRATES BAYER MATERIALSCIENCE AG (DE) 2012-05-10 US disclosed
CN-102421856-A UV-curable protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG 2012-04-18 CN disclosed
CN-101466805-A UV-curable protective layer for thermoplastic substrates BAYER MATERIALSCIENCE AG (DE) 2009-06-24 CN disclosed
US-5468789-A Devolatilization under inert atmosphere mixture containing specified anaerobic gelation inhibitors; weatherproofing thermoplastic substrates GENERAL ELECTRIC COMPANY (US) 1995-11-21 US disclosed
US-5466491-A Polymer substrate with curable coating and gelation inhibitor sensitive to radiation GENERAL ELECTRIC COMPANY (US) 1995-11-14 US disclosed
US-5318850-A A mixture consisting of silica, hydrolysis product of an alkoxysilyl acrylate, acrylate monomer having hexanediol diacrylate, isobornyl acrylate or cyclohexyl acrylate and a photoinitiators GENERAL ELECTRIC COMPANY (US) 1994-06-07 US disclosed
EP-0576247-A2 Radiation curable hardcoat compositions GENERAL ELECTRIC COMPANY (US) 1993-12-29 EP disclosed
EP-0565310-A1 Method of making a UV-curable hardcoat compositions GENERAL ELECTRIC COMPANY (US) 1993-10-13 EP disclosed
US-5242719-A Reaction of multifunctional acrylate and silyl functional acrylate and silicon dioxide GENERAL ELECTRIC COMPANY (US) 1993-09-07 US disclosed
EP-0544465-A1 UV curable abrasion-resistant coatings GENERAL ELECTRIC COMPANY (US) 1993-06-02 EP disclosed
US-4491508-A Method of preparing curable coating composition from alcohol, colloidal silica, silylacrylate and multiacrylate monomer GENERAL ELECTRIC COMPANY (US) 1985-01-01 US disclosed
US-4455205-A ULTRAVIOLET RADIATION, WEAR RESISTANCE COATINGS GENERAL ELECTRIC COMPANY (US) 1984-06-19 US disclosed