Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PYGL | P06737 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857854 | 0.87 | KDM4C (0.66) | KMT2APKMALDH1A1KDM4EMEN1 | |
| SCHEMBL13593266 | 0.86 | KMT2A (0.61) | KMT2APKMALDH1A1KDM4EMEN1 | |
| SCHEMBL16221621 | 0.85 | KMT2A (0.59) | KMT2APKMALDH1A1KDM4EMEN1 | |
| SCHEMBL8857426 | 0.84 | POLB (0.48) | KMT2APKMALDH1A1KDM4EMEN1 | |
| SCHEMBL11060481 | 0.83 | KMT2A (0.58) | KMT2APKMALDH1A1KDM4EMEN1 | |
| SCHEMBL14392276 | 0.83 | KMT2A (0.58) | KMT2APKMALDH1A1KDM4EMEN1 | |
| SCHEMBL7529550 | 0.82 | KMT2A (0.56) | KMT2APKMALDH1A1KDM4EMEN1 | |
| SCHEMBL729994 | 0.81 | SMN1; SMN2 (0.70) | KMT2APKMALDH1A1KDM4EMEN1 | |
| SCHEMBL2128835 | 0.81 | ALDH1A1 (0.68) | KMT2APKMALDH1A1KDM4EMEN1 | |
| SCHEMBL30772316 | 0.80 | KMT2A (0.67) | KMT2APKMALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914460-B1 | VEHICLE FOR THE TRANSPORT OF MOLECULAR SUBSTANCES | NOVEMBER AG MOLEKULARE MEDIZIN (DE) | 2003-04-02 | — | — | EP | claimed |
| US-6165772-A | Vehicle for the transport of molecular substances | RESPONSIF GMBH (DE) | 2000-12-26 | — | — | US | claimed |
| EP-1007107-A2 | METHOD FOR TRANSPORTING A MOLECULAR SUBSTANCE IN PREDETERMINED AREAS OF EUCARYOTIC CELLS | november Aktiengesellschaft Gesellschaft für Molekulare Medizin (DE) | 2000-06-14 | — | — | EP | claimed |
| WO-2000000224-A2 | METHOD FOR TRANSPORTING A MOLECULAR SUBSTANCE IN PREDETERMINED AREAS OF EUCARYOTIC CELLS | NOVEMBER AG NOVUS MEDICATUS BERTLING GESELLSCHAFT FÜR MOLEKULARE MEDIZIN (DE) | 2000-01-06 | — | — | WO | claimed |
| US-9470680-B2 | Fluorescence-based approach to monitor release factor-catalyzed termination of protein synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-10-18 | — | — | US | disclosed |
| EP-1543329-B1 | CELL-BASED FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET) ASSAYS FOR CLOSTRIDIAL TOXINS | ALLERGAN INC (US) | 2016-08-03 | — | — | EP | disclosed |
| US-20130034914-A1 | FLUORESCENCE-BASED APPROACH TO MONITOR RELEASE FACTOR-CATALYZED TERMINATION OF PROTEIN SYNTHESIS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-02-07 | — | — | US | disclosed |
| EP-1438586-B1 | FRET PROTEASE ASSAYS FOR CLOSTRIDIAL TOXINS | ALLERGAN INC (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-1901069-B1 | Fret protease assays for clostridial toxins | ALLERGAN INC (US) | 2012-01-04 | — | — | EP | disclosed |
| US-8053209-B2 | FRET protease assays for clostridial toxins | ALLERGAN, INC. (US) | 2011-11-08 | — | — | US | disclosed |
| US-8053208-B2 | FRET protease assays for clostridial toxins | ALLERGAN, INC. (US) | 2011-11-08 | — | — | US | disclosed |
| US-8048643-B2 | FRET protease assays for clostridial toxins | ALLERGAN, INC. (US) | 2011-11-01 | — | — | US | disclosed |
| EP-1107979-A2 | LIPID MATRIX-ASSISTED CHEMICAL LIGATION AND SYNTHESIS OF MEMBRANE POLYPEPTIDES | Gryphon Sciences (US) | 2001-06-20 | — | — | EP | disclosed |
| US-6165772-A | Vehicle for the transport of molecular substances | RESPONSIF GMBH (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-1009757-A1 | MODULAR PROTEIN LIBRARIES AND METHODS OF PREPARATION | Gryphon Sciences (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000012536-A2 | LIPID MATRIX-ASSISTED CHEMICAL LIGATION AND SYNTHESIS OF MEMBRANE POLYPEPTIDES | GRYPHON SCIENCES (US) | 2000-03-09 | — | — | WO | disclosed |
| WO-1999011655-A1 | MODULAR PROTEIN LIBRARIES AND METHODS OF PREPARATION | GRYPHON SCIENCES (US) | 1999-03-11 | — | — | WO | disclosed |
| EP-0537981-B1 | Cleavage method for acyl thiohydantoins and use of the method in C-terminal peptide sequencing | PERKIN ELMER CORP (US) | 1998-06-03 | — | — | EP | disclosed |
| EP-0537981-A2 | Cleavage method for acyl thiohydantoins and use of the method in C-terminal peptide sequencing | THE PERKIN-ELMER CORPORATION (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5185266-A | Cleaving an alkylated thiohydantoin adduct from a peptide under anhydrous, acidic conditions and analyzing the side chain of the amino acid | APPLIED BIOSYSTEMS, INC. (US) | 1993-02-09 | — | — | US | disclosed |