Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633247 | 0.89 | MAPT (0.53) | ALDH1A1MAPTLMNACYP11B2ACACB | |
| SCHEMBL16665290 | 0.86 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19633241 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNACYP11B2MEN1 | |
| SCHEMBL19633455 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNACYP11B2ACACB | |
| SCHEMBL28945679 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNACYP11B2GPR119 | |
| SCHEMBL24794212 | 0.82 | MAPT (0.52) | ALDH1A1MAPTLMNACYP11B2ACACB | |
| SCHEMBL30082676 | 0.82 | MAPT (0.52) | ALDH1A1MAPTLMNACYP11B2ACACB | |
| SCHEMBL5234962 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL17411129 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNACYP11B2MEN1 | |
| SCHEMBL24794275 | 0.81 | MAPT (0.56) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018130-A1 | Pyrimidine Derivative, Method For Preparing Same And Use Thereof In Medicine | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2024-01-18 | — | — | US | disclosed |
| US-11827625-B2 | Pyrimidine derivative, method for preparing same and use thereof in medicine | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. | 2023-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827625-B2 | Pyrimidine derivative, method for preparing same and use thereof in medicine | FGFR4, FGFR1, FGFR2 | ALDH1A1 1084/4885MAPT 2403/4885LMNA 4760/4885 |
| US-20240018130-A1 | Pyrimidine Derivative, Method For Preparing Same And Use Thereof In Medicine | FGFR4, FGFR1, FGFR2 | ALDH1A1 1084/4885MAPT 2403/4885LMNA 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.