SCHEMBL26803151

SCHEMBL26803151

COC(C)Cc1cnco1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.34
NAMPT P43490 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3137449 0.71
SCHEMBL14268249 0.71 ACACB (0.38) ACACBNAMPT
SCHEMBL22407911 0.69 CYP3A4 (0.36) ACACB
SCHEMBL9854810 0.68 TSHR (0.32) ACACB
SCHEMBL1016848 0.68
SCHEMBL28318874 0.65 ACACB (0.30) ACACB
SCHEMBL20937684 0.65 LMNA (0.37)
SCHEMBL29203478 0.64 NAMPT (0.38) NAMPT
SCHEMBL21466492 0.64
SCHEMBL20809614 0.63 NAMPT (0.37) ACACBNAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023230609-A1 HETEROCYCLIC PAD4 INHIBITORS CELGENE CORPORATION (US) 2023-11-30 WO disclosed
WO-2023230612-A1 HETEROCYCLIC PAD4 INHIBITORS CELGENE CORPORATION (US) 2023-11-30 WO disclosed