Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681822 | 0.95 | MCHR1 (0.41) | F10ACKR3MCHR1HTR2CIKBKE | |
| SCHEMBL1727318 | 0.91 | MCHR1 (0.44) | ACKR3MCHR1HTR2CHDAC1 | |
| SCHEMBL2680635 | 0.88 | F10 (0.43) | F10ACKR3MCHR1HTR2CTBK1 | |
| SCHEMBL2681546 | 0.88 | ACHE (0.37) | F10MCHR1HTR2CIKBKETBK1 | |
| SCHEMBL4442622 | 0.86 | HDAC4 (0.34) | F10MCHR1MEN1KMT2AHDAC1 | |
| SCHEMBL2682590 | 0.86 | F10 (0.42) | F10ACKR3MCHR1HTR2CTBK1 | |
| SCHEMBL2681297 | 0.86 | F10 (0.40) | F10MCHR1HTR2CTBK1KMT2A | |
| SCHEMBL2681885 | 0.85 | F10 (0.44) | F10BRAFHIF1AEPAS1MEN1 | |
| Hydrochloric Acid SCHEMBL2681741 | 0.85 | F10 (0.43) | F10BRAFHIF1AEPAS1MEN1 | |
| SCHEMBL4402603 | 0.84 | GPR6 (0.43) | F10MCHR1HTR2CHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451801-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| EP-2451801-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| US-8586593-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120115884-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115884-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115884-A1 | INSECTICIDAL COMPOUNDS | ACHE, C1R, C5 | F10 1116/4885ACKR3 1584/4885MCHR1 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.