SCHEMBL26809663

SCHEMBL26809663

c1ccc2c(c1)ccc1c3cc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7ccc8ccc9c%10ccccc%10ccc9c8c7)c6c54)ccc3ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.47
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 3/20 0.44
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
CYP1A2 P05177 3/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
CYP2A6 P11509 1/20 0.40
TSHR P16473 1/20 0.40
PAX8 Q06710 1/20 0.36
HPGD P15428 1/20 0.35
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
APEX1 P27695 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26809660 0.95 HPRT1 (0.42) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL18086247 0.94 KDM4E (0.52) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL26809537 0.94 ALDH1A1 (0.41) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL17358412 0.91 HPRT1 (0.52) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL18086212 0.88 KDM4E (0.54) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL17228249 0.87 KDM4E (0.52) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL17864186 0.86 KDM4E (0.51) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL20311570 0.86 HPRT1 (0.40) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL10027551 0.86 KDM4E (0.44) ALDH1A1KDM4EATML3MBTL1TDP1
SCHEMBL17448878 0.86 KDM4E (0.40) HPRT1ALDH1A1HSD17B10HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389418-A1 MATERIAL OF PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING, AND PHOTOELECTRIC CONVERSION ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-30 US disclosed
US-20230389418-A1 MATERIAL OF PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING, AND PHOTOELECTRIC CONVERSION ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-30 US disclosed