SCHEMBL26809685

SCHEMBL26809685

CCc1oc2ccc(Cl)cc2c1C(=O)c1cc(I)c(O)c(I)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 8/20 0.71
EYA3 Q99504 7/20 0.71
MEN1 O00255 2/20 0.71
ABCB11 O95342 2/20 0.71
LMNA P02545 2/20 0.71
PGR P06401 2/20 0.71
ADRA2A P08913 2/20 0.71
TBXA2R P21731 2/20 0.71
OPRM1 P35372 2/20 0.71
SLC6A3 Q01959 2/20 0.71
KMT2A Q03164 2/20 0.71
BIRC5 O15392 1/20 0.71
HTR1A P08908 1/20 0.71
DRD1 P21728 1/20 0.71
PTGS1 P23219 1/20 0.71
SLC6A2 P23975 1/20 0.71
PDE4A P27815 1/20 0.71
ADORA1 P30542 1/20 0.71
DRD3 P35462 1/20 0.71
HRH3 Q9Y5N1 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30357402 1.00 TTR (0.71) TTREYA3MEN1ABCB11LMNA
SCHEMBL29286597 0.90 TTR (0.59) TTREYA3MEN1ABCB11LMNA
SCHEMBL26809640 0.90 TTR (0.77) TTREYA3MEN1ABCB11LMNA
SCHEMBL25390776 0.88 EYA3 (0.73) TTREYA3MEN1ABCB11LMNA
SCHEMBL30357412 0.86 SLC22A12 (0.78) TTREYA3MEN1ABCB11LMNA
SCHEMBL6336510 0.86 SLC22A12 (0.78) TTREYA3MEN1ABCB11LMNA
SCHEMBL26809743 0.86 TTR (0.73) TTREYA3MEN1ABCB11LMNA
SCHEMBL30258777 0.85 TTR (0.71) TTREYA3MEN1ABCB11LMNA
SCHEMBL6336521 0.85 SLC22A12 (0.80) TTREYA3MEN1ABCB11LMNA
SCHEMBL26668803 0.84 TTR (0.51) TTREYA3MEN1ABCB11LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023229099-A1 BENZOFURANYL HYDROXYPHENYL METHANONE OXIME DERIVATIVE AND USES THEREOF (주)이노보테라퓨틱스 2023-11-30 WO disclosed