SCHEMBL26812751

SCHEMBL26812751

CC(C)c1c(F)cc(N2CCOC[C@@H]2C(F)(F)F)cc1CN1CCOCC1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 12/20 0.41
CYP2A13 Q16696 1/20 0.37
KCNH2 Q12809 5/20 0.36
MAPT P10636 1/20 0.34
NR1H2 P55055 1/20 0.34
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
PIK3CG P48736 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26812741 0.93 PIK3C3 (0.39) PIK3C3KCNH2NR1H2PIK3CAPIK3CB
SCHEMBL26812747 0.86 PIK3C3 (0.48) PIK3C3PIK3CAPIK3CBPIK3CG
SCHEMBL26812752 0.82 PIK3C3 (0.45) PIK3C3PIK3CAPIK3CBPIK3CG
SCHEMBL21756936 0.73 CYP2A13 (0.47) CYP2A13KCNH2MAPT
SCHEMBL26812028 0.71 CYP2A13 (0.40) CYP2A13KCNH2MAPT
SCHEMBL26812754 0.70 PIK3C3 (0.50) PIK3C3
SCHEMBL27410325 0.70 PIK3C3 (0.44) PIK3C3PIK3CAPIK3CBPIK3CG
SCHEMBL24721330 0.69 PIK3C3 (0.44) PIK3C3MAPTPIK3CAPIK3CBPIK3CG
SCHEMBL21977884 0.69 PIK3C3 (0.47) PIK3C3PIK3CAPIK3CBPIK3CG
SCHEMBL21955036 0.69 PIK3C3 (0.47) PIK3C3PIK3CAPIK3CBPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023220741-A1 ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF DICE MOLECULES SV, INC. (US) 2023-11-16 WO disclosed