SCHEMBL268157

SCHEMBL268157

Cc1cc(C=O)c(N)c(O)c1CCl

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 10/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL267265 0.87 ERN1 (0.40) ERN1
SCHEMBL268061 0.80 ALDH1A1 (0.30)
SCHEMBL268809 0.78 ALDH1A1 (0.33) ERN1
SCHEMBL267180 0.77
SCHEMBL269847 0.75 ALDH1A1 (0.34) ERN1
SCHEMBL268342 0.71
SCHEMBL6842711 0.69 ERN1 (0.52) ERN1
SCHEMBL31346731 0.67 ERN1 (0.48) ERN1
SCHEMBL29110863 0.67 ALDH1A1 (0.33) ERN1
SCHEMBL28739771 0.67 ERN1 (0.48) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8134015-B2 Compound inhibiting in vivo phosphorous transport and medicine containing the same KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-03-13 US disclosed