SCHEMBL26819600

SCHEMBL26819600

Clc1nc(-c2cccc(-c3ccc4c5ccccc5c5ccccc5c4c3)c2)c2oc3ccc(-c4ccccc4)cc3c2n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.47
CSNK2A2 P19784 2/20 0.47
CSNK2B P67870 2/20 0.47
PIM3 Q86V86 2/20 0.47
PIM2 Q9P1W9 2/20 0.47
PLA2G2A P14555 4/20 0.38
PLA2G4A P47712 4/20 0.38
PLA2G10 O15496 1/20 0.38
ALDH1A1 P00352 6/20 0.38
MAPT P10636 4/20 0.38
HPGD P15428 3/20 0.38
LMNA P02545 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GAA P10253 2/20 0.38
POLB P06746 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PRKDC P78527 1/20 0.37
RXFP1 Q9HBX9 1/20 0.36
ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26819616 0.96 PIM1 (0.46) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL30493208 0.90 PIM1 (0.53) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL24388223 0.90 PIM1 (0.53) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL24388212 0.90 PIM1 (0.53) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL24388410 0.89 PIM1 (0.47) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL26819636 0.89 PIM1 (0.39) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL17297451 0.89 ADORA2A (0.44) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL26818920 0.88 PIM1 (0.44) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL26818864 0.88 PIM1 (0.44) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL26818882 0.88 ALDH1A1 (0.45) PIM1CSNK2A2CSNK2BPIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389344-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2023-11-30 US disclosed
US-20230389344-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2023-11-30 US disclosed