SCHEMBL26820141

SCHEMBL26820141

Fc1ccc(-c2ccc(-c3ccc(-c4ccc5ccccc5c4)cc3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.65
CYP2A6 P11509 1/20 0.65
ESR1 P03372 4/20 0.61
ESR2 Q92731 4/20 0.61
ALOX5 P09917 1/20 0.54
HSD17B1 P14061 1/20 0.52
HSD17B2 P37059 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
GSTP1 P09211 1/20 0.50
PGR P06401 1/20 0.48
CYP17A1 P05093 1/20 0.48
CYP19A1 P11511 1/20 0.48
CYP11B1 P15538 1/20 0.48
CYP11B2 P19099 1/20 0.48
LPL P06858 1/20 0.46
LIPG Q9Y5X9 1/20 0.46
NR3C1 P04150 1/20 0.45
ACMSD Q8TDX5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29991808 1.00 CYP1A2 (0.65) CYP1A2CYP2A6ESR1ESR2ALOX5
SCHEMBL7643326 1.00 CYP1A2 (0.65) CYP1A2CYP2A6ESR1ESR2ALOX5
SCHEMBL26548373 1.00 CYP1A2 (0.65) CYP1A2CYP2A6ESR1ESR2ALOX5
SCHEMBL26547919 1.00 CYP1A2 (0.65) CYP1A2CYP2A6ESR1ESR2ALOX5
SCHEMBL11469524 1.00 CYP1A2 (0.65) CYP1A2CYP2A6ESR1ESR2ALOX5
SCHEMBL26548549 0.98 CYP1A2 (0.62) CYP1A2CYP2A6ESR1ESR2ALOX5
SCHEMBL26548863 0.98 CYP1A2 (0.62) CYP1A2CYP2A6ESR1ESR2ALOX5
SCHEMBL26564493 0.91 ESR1 (0.59) CYP1A2CYP2A6ESR1ESR2HSD17B1
SCHEMBL26548510 0.90 PGR (0.55) CYP1A2CYP2A6ESR1ESR2CA2
SCHEMBL26548124 0.90 PGR (0.55) CYP1A2CYP2A6ESR1ESR2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4282861-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-11-29 EP disclosed