Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 2/20 | 0.47 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | VHL | P40337 | 9/20 | 0.38 |
| ▸ | ELOC | Q15369 | 5/20 | 0.38 |
| ▸ | ELOB | Q15370 | 5/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374525 | 0.88 | VHL (0.39) | ELANEVHLELOCELOB | |
| SCHEMBL30847613 | 0.87 | VHL (0.39) | ELANEVHLELOCELOB | |
| SCHEMBL27374522 | 0.87 | VHL (0.39) | ELANEVHLELOCELOB | |
| SCHEMBL12055223 | 0.83 | PEPD (0.49) | PEPDXPNPEP1POLBFKBP1AELANE | |
| SCHEMBL7804414 | 0.81 | ELANE (0.56) | PEPDXPNPEP1POLBFKBP1AELANE | |
| SCHEMBL13748696 | 0.81 | ELANE (0.56) | PEPDXPNPEP1POLBFKBP1AELANE | |
| SCHEMBL24837712 | 0.81 | VHL (0.53) | VHLELOCELOB | |
| SCHEMBL28654528 | 0.81 | VHL (0.53) | VHLELOCELOB | |
| SCHEMBL8253230 | 0.80 | PEPD (0.51) | PEPDXPNPEP1POLBFKBP1AELANE | |
| SCHEMBL8046113 | 0.80 | KLK5 (0.51) | PEPDXPNPEP1POLBFKBP1AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |