Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.56 |
| ▸ | PEPD | P12955 | 3/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | XPNPEP1 | Q9NQW7 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 4/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748696 | 1.00 | ELANE (0.56) | ELANEPEPDFKBP1AXPNPEP1POLB | |
| SCHEMBL12055223 | 0.87 | PEPD (0.49) | ELANEPEPDFKBP1AXPNPEP1POLB | |
| SCHEMBL8144172 | 0.86 | ELANE (0.54) | ELANEPEPDCTSVCTSLCTSB | |
| SCHEMBL8253230 | 0.84 | PEPD (0.51) | ELANEPEPDFKBP1AXPNPEP1POLB | |
| SCHEMBL14202917 | 0.84 | KLK5 (0.51) | ELANEPEPDFKBP1AXPNPEP1POLB | |
| SCHEMBL8046113 | 0.84 | KLK5 (0.51) | ELANEPEPDFKBP1AXPNPEP1POLB | |
| SCHEMBL8252703 | 0.83 | PEPD (0.50) | ELANEPEPDFKBP1AXPNPEP1POLB | |
| SCHEMBL8274097 | 0.81 | PEPD (0.45) | ELANEPEPDFKBP1AXPNPEP1POLB | |
| SCHEMBL26825564 | 0.81 | PEPD (0.47) | ELANEPEPDFKBP1AXPNPEP1POLB | |
| SCHEMBL16313141 | 0.80 | ELANE (0.42) | ELANEPEPDFKBP1AXPNPEP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138889-A1 | PEPTIDES FOR THE TREATMENT OF HCV INFECTIONS | CONCERT PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |
| WO-2006130628-A2 | COMBINATION OF HCV PROTEASE INHIBITORS WITH A SURFACTANT | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |