⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630858 | 0.84 | GRIN2D (0.44) | — | |
| SCHEMBL1836255 | 0.80 | — | — | |
| SCHEMBL1542339 | 0.78 | — | — | |
| SCHEMBL9246531 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL3020906 | 0.78 | — | — | |
| Methane SCHEMBL29028971 | 0.76 | PGK1 (0.34) | — | |
| SCHEMBL31724734 | 0.76 | MAPT (0.38) | — | |
| Methane SCHEMBL29017612 | 0.76 | CCR1 (0.43) | — | |
| Methane SCHEMBL7335736 | 0.76 | PARP1 (0.40) | — | |
| SCHEMBL4273312 | 0.76 | KCNH2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230542-A2 | PYRAZOLO[1,5-a]PYRIDINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |