Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27705336 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL27688877 | 1.00 | — | — | |
| Bicarbonate SCHEMBL27586070 | 1.00 | — | — | |
| Bicarbonate SCHEMBL17421 | 1.00 | — | — | |
| Bicarbonate SCHEMBL11896253 | 1.00 | — | — | |
| Bicarbonate SCHEMBL9772345 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2987016 | 0.94 | CA1 (0.62) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL6541110 | 0.94 | — | — | |
| Bicarbonate SCHEMBL15401809 | 0.94 | — | — | |
| Bicarbonate SCHEMBL12500505 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2285 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106133034-B | Polyvinyl alcohol fibers and films with mineral fillers and small cellulose particles | GPCP知识产权控股有限责任公司 | 2019-11-12 | — | — | CN | claimed |
| CN-107022924-B | A kind of maceration extract and its transparency paper of preparation and the method for quickly preparing transparency paper | 华南理工大学 | 2019-10-18 | — | — | CN | claimed |
| CN-107022925-B | A kind of maceration extract and its height of preparation quantify transparency paper and the quickly method of the high quantitative transparency paper of preparation | 华南理工大学 | 2019-10-18 | — | — | CN | claimed |
| CN-107119496-B | A kind of maceration extract and its quick application for preparing the method for transparency paper and the transparency paper of preparation | 华南理工大学 | 2019-10-18 | — | — | CN | claimed |
| CN-110331836-A | A kind of novel sanding floor and its production technology | 江苏蓝圈新材料股份有限公司 | 2019-10-15 | — | — | CN | claimed |
| CN-110184029-A | A kind of peanut meal base albumen adhesive and its preparation method and application | 山东省农业科学院农业质量标准与检测技术研究所 | 2019-08-30 | — | — | CN | claimed |
| CN-106430920-B | The preparation method and quartz glass of quartz glass | 中国建筑材料科学研究总院 | 2019-08-13 | — | — | CN | claimed |
| CN-107893226-B | A kind of water-based antirust agent improving screw thread steel concrete bond property | 汉高乐泰(宁夏)新材料有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-110073056-A | The coating composition of oil resistant rouge, oil resistant and water resistant | 太阳化学公司 | 2019-07-30 | — | — | CN | claimed |
| CN-110002752-A | A kind of chemically toughened glass and preparation method | 陕西拓日新能源科技有限公司 | 2019-07-12 | — | — | CN | claimed |
| CN-1511908-A | Water resin composition for treating steel plate coated with aluminium-zinc alloy, its coating method and steel plate coated with aluminium-zinc alloy | 日本油漆株式会社 | 2004-07-14 | — | — | CN | claimed |
| CN-1507476-A | Colorants Encapsulated in a Polymer Matrix | �Ϻ���ͨ��ѧ | 2004-06-23 | — | — | CN | claimed |
| CN-1474751-A | Heat sensitive recording sheet and use of the same | ������¼���ֽҵ����˹������˾ | 2004-02-11 | — | — | CN | claimed |
| CN-1456484-A | Catering service article coating | NAT STARCH CHEM INVEST (US) | 2003-11-19 | — | — | CN | claimed |
| CN-1442578-A | Production method of paper for low gram weight vacuum steam coating aluminium | JINDONG PAPER INDUSTRY JIANGSU (CN) | 2003-09-17 | — | — | CN | claimed |
| CN-1102110-C | Direct thermal lithographic printing plate and method for manufacturing the same | ASAHI CHEMICAL IND (JP) | 2003-02-26 | — | — | CN | claimed |
| CN-1335870-A | Method for producing products from natural polymers and products produced thereby | VERTIS BV (NL) | 2002-02-13 | — | — | CN | claimed |
| CN-1068362-C | Original dye applied with mixture of phosphate of zirconium or titanic | CIBA SC HOLDING AB (CH) | 2001-07-11 | — | — | CN | claimed |
| CN-1124260-A | Original dye applied with mixture of phosphate of zirconium or titanic | CIBA GEIGY CORP (CH) | 1996-06-12 | — | — | CN | claimed |
| CN-1093379-A | Latex for heat-resistant inks | HENKEL CORP (US) | 1994-10-12 | — | — | CN | claimed |