Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27688877 | 1.00 | — | — | |
| Bicarbonate SCHEMBL27586070 | 1.00 | — | — | |
| Bicarbonate SCHEMBL17421 | 1.00 | — | — | |
| Bicarbonate SCHEMBL11896253 | 1.00 | — | — | |
| Bicarbonate SCHEMBL26829 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL9772345 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2987016 | 0.94 | CA1 (0.62) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL6541110 | 0.94 | — | — | |
| Bicarbonate SCHEMBL15401809 | 0.94 | — | — | |
| Bicarbonate SCHEMBL12500505 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109742393-A | A kind of preparation method of NCM811 type ternary material | 广州中卓智能装备有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-109742392-A | A kind of Preparation equipment of NCM811 type ternary material and method using equipment production NCM811 type ternary material | 广州中卓智能装备有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-102892944-A | Method of forming crosslinked superabsorbent polymers on a substrate and uses thereof | H & R CHEMPHARM UK LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-101208268-B | Process for production of alkaline zirconia sol | NISSAN CHEMICAL IND LTD | 2010-12-29 | — | — | CN | disclosed |
| CN-101213037-B | Processes for production of slurries and molds for precision casting | NISSAN CHEMICAL IND LTD | 2010-12-01 | — | — | CN | disclosed |
| CN-101213037-A | Processes for production of slurries and molds for precision casting | NISSAN CHEMICAL IND LTD (JP) | 2008-07-02 | — | — | CN | disclosed |
| CN-101208268-A | Process for production of alkaline zirconia sol | NISSAN CHEMICAL IND LTD (JP) | 2008-06-25 | — | — | CN | disclosed |
| CN-101133212-A | Improved retention and drainage in the manufacture of paper | HERCULES INC (US) | 2008-02-27 | — | — | CN | disclosed |