Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.67 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656584 | 1.00 | SIGMAR1 (0.67) | SIGMAR1TMEM97JAK2ROCK2PRKD3 | |
| SCHEMBL26665017 | 1.00 | SIGMAR1 (0.67) | SIGMAR1TMEM97JAK2ROCK2PRKD3 | |
| SCHEMBL30656558 | 0.93 | SIGMAR1 (0.63) | SIGMAR1TMEM97TRPC5HRH3 | |
| SCHEMBL26665038 | 0.93 | SIGMAR1 (0.63) | SIGMAR1TMEM97TRPC5HRH3 | |
| SCHEMBL26829181 | 0.93 | SIGMAR1 (0.63) | SIGMAR1TMEM97TRPC5HRH3 | |
| SCHEMBL26829074 | 0.86 | SIGMAR1 (0.88) | SIGMAR1TMEM97 | |
| SCHEMBL26665048 | 0.86 | SIGMAR1 (0.88) | SIGMAR1TMEM97 | |
| SCHEMBL30656608 | 0.86 | SIGMAR1 (0.88) | SIGMAR1TMEM97 | |
| SCHEMBL30656578 | 0.83 | SIGMAR1 (0.58) | SIGMAR1TMEM97ACHEFFAR4 | |
| SCHEMBL26665062 | 0.83 | SIGMAR1 (0.58) | SIGMAR1TMEM97ACHEFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225563-A2 | SELECTIVE SIGMA-2 RECEPTOR LIGANDS AS MODULATORS OF TMEM97 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-11-23 | — | — | WO | disclosed |