Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 2/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | IKBKB | O14920 | 4/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13035810 | 0.82 | AKT2 (0.67) | AKT2CHEK1IKBKBIKBKEACVR1 | |
| SCHEMBL20213984 | 0.79 | AKT2 (0.62) | AKT2CHEK1IKBKBIKBKEACVR1 | |
| SCHEMBL16115987 | 0.79 | IKBKB (0.71) | AKT2CHEK1IKBKBIKBKEACVR1 | |
| SCHEMBL30829475 | 0.79 | AKT2 (0.62) | AKT2CHEK1IKBKBIKBKEACVR1 | |
| SCHEMBL873114 | 0.77 | AKT2 (1.00) | AKT2CHEK1IKBKBIKBKEACVR1 | |
| SCHEMBL24732319 | 0.77 | CHEK1 (0.59) | AKT2CHEK1IKBKBIKBKEACVR1 | |
| SCHEMBL24765276 | 0.77 | CHEK1 (0.59) | AKT2CHEK1IKBKEROCK2ROCK1 | |
| SCHEMBL26834432 | 0.77 | AKT2 (0.59) | AKT2CHEK1IKBKBIKBKEACVR1 | |
| SCHEMBL15653783 | 0.76 | AKT2 (0.57) | AKT2CHEK1IKBKBIKBKEACVR1 | |
| SCHEMBL16209719 | 0.75 | AKT2 (0.79) | AKT2CHEK1IKBKBACVR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024057020-A1 | ANTI-VIRAL COMPOUNDS | Infex Therapeutics Limited (GB) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023223055-A1 | ANTI-VIRAL COMPOUNDS | Infex Therapeutics Limited (GB) | 2023-11-23 | — | — | WO | disclosed |