Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 8/20 | 0.37 |
| ▸ | CNR1 | P21554 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2683632 | 1.00 | NR1I2 (0.46) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL10300850 | 1.00 | NR1I2 (0.46) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL8516742 | 0.89 | NR1I2 (0.60) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL6973425 | 0.88 | NR1I2 (0.52) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL11793409 | 0.88 | NR1I2 (0.52) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL28569871 | 0.87 | ALDH1A1 (0.59) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL31275312 | 0.84 | NR1I2 (0.53) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL9183887 | 0.83 | NR1I2 (0.60) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL9183882 | 0.83 | NR1I2 (0.60) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL28978669 | 0.81 | NR1I2 (0.44) | NR1I2PGRADORA3PTGS2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029593-B2 | Method for manufacturing spilanthol and intermediate manufacturing product therefor | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-05-12 | — | — | US | disclosed |
| US-9029593-B2 | Method for manufacturing spilanthol and intermediate manufacturing product therefor | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-05-12 | — | — | US | disclosed |
| US-9029593-B2 | Method for manufacturing spilanthol and intermediate manufacturing product therefor | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-05-12 | — | — | US | disclosed |
| EP-2455363-B1 | METHOD FOR MANUFACTURING SPILANTHOL AND INTERMEDIATE MANUFACTURING PRODUCT THEREFOR | TAKASAGO PERFUMERY CO LTD (JP) | 2014-10-01 | — | — | EP | disclosed |
| CN-102471238-B | Method for manufacturing spilanthol and intermediate manufacturing product therefor | TAKASAGO PERFUMERY CO LTD | 2014-04-02 | — | — | CN | disclosed |
| EP-2455363-A1 | METHOD FOR MANUFACTURING SPILANTHOL AND INTERMEDIATE MANUFACTURING PRODUCT THEREFOR | Takasago International Corporation (JP) | 2012-05-23 | — | — | EP | disclosed |
| EP-2455363-A1 | METHOD FOR MANUFACTURING SPILANTHOL AND INTERMEDIATE MANUFACTURING PRODUCT THEREFOR | Takasago International Corporation (JP) | 2012-05-23 | — | — | EP | disclosed |
| CN-102471238-A | Process for producing spilanthol and intermediate for producing the same | TAKASAGO PERFUMERY CO LTD | 2012-05-23 | — | — | CN | disclosed |
| US-20120116116-A1 | METHOD FOR MANUFACTURING SPILANTHOL AND INTERMEDIATE MANUFACTURING PRODUCT THEREFOR | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-05-10 | — | — | US | disclosed |
| US-20120116116-A1 | METHOD FOR MANUFACTURING SPILANTHOL AND INTERMEDIATE MANUFACTURING PRODUCT THEREFOR | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-05-10 | — | — | US | disclosed |
| US-20120116116-A1 | METHOD FOR MANUFACTURING SPILANTHOL AND INTERMEDIATE MANUFACTURING PRODUCT THEREFOR | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116116-A1 | METHOD FOR MANUFACTURING SPILANTHOL AND INTERMEDIATE MANUFACTURING PRODUCT THEREFOR | CYP4A11, CYP4F8, CYP51A1 | NR1I2 3042/4885PGR 2232/4885ADORA3 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.