Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.77 |
| ▸ | HTR2C | P28335 | 5/20 | 0.77 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718518 | 0.89 | HTR2A (0.62) | HTR2AHTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL26675916 | 0.89 | HTR2A (0.77) | HTR2AHTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL970777 | 0.87 | HTR2A (1.00) | HTR2AHTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL6718656 | 0.86 | HTR2A (0.58) | HTR2AHTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL6716207 | 0.86 | HTR2A (0.58) | HTR2AHTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL6712409 | 0.85 | HTR2A (0.57) | HTR2AHTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL6713595 | 0.85 | HTR2A (0.57) | HTR2AHTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL7097243 | 0.84 | HTR2A (0.58) | HTR2AHTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL7097239 | 0.84 | HTR2A (0.58) | HTR2AHTR2CHTR1AHTR1DHTR1B | |
| SCHEMBL6718700 | 0.83 | HTR2A (0.55) | HTR2AHTR2CHTR1BADRB1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382919-A1 | OXA- IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382919-A1 | OXA- IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GRIA4, GRIA3, GRIN3A | HTR2A 133/4885HTR2C 126/4885HTR1A 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.