Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 2/20 | 0.37 |
| ▸ | SKP1 | P63208 | 2/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21060267 | 0.90 | MAP4K4 (0.54) | MAP4K4CKS1BSKP1SKP2GPR119 | |
| SCHEMBL30675155 | 0.90 | MAP4K4 (0.54) | MAP4K4CKS1BSKP1SKP2GPR119 | |
| SCHEMBL26844190 | 0.86 | MAP4K4 (0.41) | MAP4K4ATRGRM2PARP1GPR119 | |
| SCHEMBL21060019 | 0.81 | MAP4K4 (0.46) | MAP4K4CKS1BSKP1SKP2PDE10A | |
| SCHEMBL30675193 | 0.81 | MAP4K4 (0.46) | MAP4K4CKS1BSKP1SKP2PDE10A | |
| SCHEMBL21060496 | 0.80 | HTR6 (0.37) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL29897149 | 0.80 | HTR6 (0.37) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL21060471 | 0.79 | HSP90AA1 (0.40) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL29897152 | 0.79 | HSP90AA1 (0.40) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL21060073 | 0.78 | HTR6 (0.36) | GPR119PIM1MARK3MAP4K2CAMK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820768-B2 | 4-azaindole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820768-B2 | 4-azaindole compounds | TLR7, TLR9, TLR5 | MAP4K4 1738/4885ATR 2614/4885CKS1B 2367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.