Bisphenol A

Bisphenol A

SCHEMBL268449

CC(C)(c1ccc(O)cc1)c1ccc(O)cc1.CC(C)(c1ccc(O)cc1)c1ccc(O)cc1.CCC(c1ccc(O)cc1)c1ccc(O)cc1.CCC(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.61
ESR2 Q92731 10/20 0.61
CYP3A4 P08684 4/20 0.61
AR P10275 2/20 0.61
SLC6A2 P23975 2/20 0.61
SLC6A3 Q01959 2/20 0.61
HPGD P15428 1/20 0.61
TSHR P16473 1/20 0.61
SLC6A4 P31645 1/20 0.61
HTR6 P50406 1/20 0.61
ESRRG P62508 1/20 0.61
HSD17B10 Q99714 1/20 0.61
ALDH1A1 P00352 2/20 0.59
LMNA P02545 2/20 0.50
CYP1A2 P05177 1/20 0.50
PGR P06401 1/20 0.50
CHRM2 P08172 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6508822 0.95 ESR1 (0.69) ESR1ESR2CYP3A4ARSLC6A2
SCHEMBL5857901 0.89 ESR1 (0.59) ESR1ESR2CYP3A4ARSLC6A2
SCHEMBL74326 0.85 ESR1 (0.65) ESR1ESR2CYP3A4ARSLC6A2
SCHEMBL1171043 0.85 ESR1 (0.65) ESR1ESR2CYP3A4ARSLC6A2
Hydroquinone SCHEMBL28097256 0.85 ESR1 (0.65) ESR1ESR2CYP3A4ARSLC6A2
SCHEMBL28544659 0.83 ESR1 (0.62) ESR1ESR2CYP3A4ARSLC6A2
Propane SCHEMBL28264453 0.83 ESR1 (0.62) ESR1ESR2CYP3A4ARSLC6A2
Benzene SCHEMBL28219933 0.83 ESR1 (0.62) ESR1ESR2CYP3A4ARSLC6A2
SCHEMBL6428218 0.83 ALOX15 (0.56) ESR1ESR2CYP3A4ARSLC6A2
SCHEMBL9051423 0.82 ESR1 (0.44) ESR1ESR2CYP3A4ARSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133941-B2 Aqueous epoxy resin compositions HUNTSMAN INTERNATIONAL LLC (US) 2012-03-13 US disclosed
EP-0872505-B1 Curable compositions based on glycidyl compounds, amine hardeners and heterocyclic accelerators VANTICO GMBH & CO KG (DE) 2001-07-11 EP disclosed
WO-1998046660-A1 HARDENABLE MIXTURES MADE OF GLYCIDYL COMPOUNDS, AMINIC HARDENERS AND HETEROCYCLIC ACCELERATORS CIBA SPEZIALITÄTENCHEMIE BERGKAMEN GMBH (DE) 1998-10-22 WO disclosed
EP-0872505-A1 Curable compositions based on glycidyl compounds, amine hardeners and heterocyclic accelerators Ciba Spezialitätenchemie Bergkamen GmbH (DE) 1998-10-21 EP disclosed