⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986236 | 0.96 | — | — | |
| SCHEMBL30140405 | 0.91 | — | — | |
| SCHEMBL10068051 | 0.82 | — | — | |
| SCHEMBL15583448 | 0.81 | CA1 (0.34) | — | |
| SCHEMBL22273284 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL15583497 | 0.77 | SCN9A (0.36) | — | |
| SCHEMBL17293557 | 0.77 | — | — | |
| SCHEMBL30945184 | 0.77 | — | — | |
| SCHEMBL31369228 | 0.75 | — | — | |
| SCHEMBL15583511 | 0.75 | CA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630565-B2 | DNA-dependent protein kinase inhibitor | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2026-05-19 | — | — | US | disclosed |
| US-11820768-B2 | 4-azaindole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-21 | — | — | US | disclosed |
| US-20220242884-A1 | DNA-DEPENDENT PROTEIN KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-08-04 | — | — | US | disclosed |
| EP-3976624-A1 | DNA-DEPENDENT PROTEIN KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-04-06 | — | — | EP | disclosed |