SCHEMBL2684545

SCHEMBL2684545

CCCCCCCCc1ccc2c(nnn2CN)c1CCCCCCCC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 4/20 0.38
SLC9A1 P19634 4/20 0.37
TYR P14679 2/20 0.36
HTR2A P28223 1/20 0.34
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX5 P09917 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TLR8 Q9NR97 5/20 0.33
HCAR3 P49019 1/20 0.32
LIPG Q9Y5X9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28225051 1.00 GRM2 (0.38) GRM2SLC9A1TYRHTR2AMEN1
SCHEMBL3269772 0.94 GRM2 (0.40) GRM2SLC9A1TYRMEN1MAPT
SCHEMBL28225054 0.86 GRM2 (0.37) GRM2SLC9A1HTT
SCHEMBL28495537 0.85 GRM2 (0.32) GRM2SLC9A1MEN1TSHRKMT2A
SCHEMBL28194727 0.83 F7 (0.36) GRM2SLC9A1TYRMAPTALOX15
SCHEMBL28225062 0.83 SLC9A1 (0.33) GRM2SLC9A1TYRHTR2AMEN1
SCHEMBL28225050 0.82 GRM2 (0.35) GRM2SLC9A1
SCHEMBL29156375 0.80 SLC9A1 (0.33) GRM2SLC9A1TYRHTR2AMEN1
SCHEMBL29156689 0.80 SLC9A1 (0.33) GRM2SLC9A1TYRHTR2AMEN1
SCHEMBL29156388 0.80 SLC9A1 (0.33) GRM2SLC9A1TYRHTR2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107614754-B The manufacturing method of the evaporator of refrigerating plant 大金工业株式会社 2018-12-21 CN disclosed
EP-2104728-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2018-10-24 EP disclosed
CN-105359070-B Laminate for touch panel, and touch panel 富士胶片株式会社 2018-06-19 CN disclosed
CN-107107587-B Laminate component and touch-screen 东丽株式会社 2018-06-05 CN disclosed
US-8168573-B2 Lubricating oil composition SHELL OIL COMPANY (US) 2012-05-01 US disclosed
US-20100105590-A1 LUBRICATING OIL COMPOSITION SHOWA SHELL SEKIYU K.K. (JP) 2010-04-29 US disclosed
US-20100087348-A1 LUBRICATING OIL COMPOSITION SHELL USA, INC. 2010-04-08 US disclosed
US-20100009878-A1 LUBRICATING OIL COMPOSITION SHOWA SHELL SEKIYU K.K. (JP) 2010-01-14 US disclosed
EP-2109657-A1 LUBRICATING OIL COMPOSITION Showa Shell Sekiyu K. K. (JP) 2009-10-21 EP disclosed
EP-2104728-A2 LUBRICATING OIL COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2009-09-30 EP disclosed
WO-2008095966-A1 LUBRICATING OIL COMPOSITION SHOWA SHELL SEKIYU K.K. (JP) 2008-08-14 WO disclosed
WO-2008081287-A2 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (CH) 2008-07-10 WO disclosed
EP-0715079-B1 Refrigerating apparatus and lubricating oil composition SANYO ELECTRIC CO (JP) 2003-02-12 EP disclosed
US-5806336-A Refrigeration apparatus and lubricating oil composition SANYO ELECTRIC CO., LTD. (JP) 1998-09-15 US disclosed
US-5557944-A USING A HYDROFLUOROCARBON SYSTEM REFRIGERANT WITH A POLYOL ESTER SYSTEM OIL SANYO ELECTRIC CO., LTD. (JP) 1996-09-24 US disclosed
EP-0715079-A2 Refrigerating apparatus and lubricating oil composition SANYO ELECTRIC CO. LTD (JP) 1996-06-05 EP disclosed