Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25123080 | 0.85 | MEN1 (0.39) | — | |
| SCHEMBL18611819 | 0.80 | CYP2C19 (0.38) | CES2CYP2C19EPHX2 | |
| SCHEMBL18592232 | 0.79 | KDM4E (0.38) | CES2CYP2C19EPHX2 | |
| SCHEMBL20046520 | 0.78 | CES2 (0.39) | CES2CYP2C19EPHX2 | |
| SCHEMBL20234764 | 0.77 | CYP2C19 (0.39) | CES2CYP2C19EPHX2 | |
| SCHEMBL20234681 | 0.77 | CES2 (0.34) | CES2CYP2C19EPHX2 | |
| SCHEMBL20443696 | 0.75 | MEN1 (0.37) | CES2CYP2C19EPHX2 | |
| SCHEMBL25773456 | 0.75 | CES2 (0.38) | CES2CYP2C19EPHX2 | |
| SCHEMBL21933179 | 0.75 | MEN1 (0.41) | CES2CYP2C19EPHX2 | |
| SCHEMBL19599821 | 0.75 | KDM4E (0.40) | CES2CYP2C19EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834460-B2 | Imide-based modulators of proteolysis and associated methods of use | YALE UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834460-B2 | Imide-based modulators of proteolysis and associated methods of use | CRBN, MDM2, UBE2N | CES2 2334/4885CYP2C19 4389/4885EPHX2 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.