Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 0.73 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26852640 | 0.96 | TOP1 (0.72) | TOP1SLC2A1 | |
| SCHEMBL26275980 | 0.94 | TOP1 (0.83) | TOP1SLC2A1 | |
| SCHEMBL26852565 | 0.94 | SLC2A1 (0.74) | TOP1SLC2A1 | |
| SCHEMBL26295772 | 0.93 | TOP1 (0.72) | TOP1SLC2A1 | |
| SCHEMBL21591945 | 0.91 | TOP1 (0.79) | TOP1SLC2A1 | |
| SCHEMBL26852547 | 0.90 | TOP1 (0.81) | TOP1SLC2A1 | |
| SCHEMBL23255613 | 0.90 | TOP1 (0.87) | TOP1SLC2A1 | |
| SCHEMBL26294990 | 0.90 | SLC2A1 (0.72) | TOP1SLC2A1 | |
| SCHEMBL21450472 | 0.89 | TOP1 (0.79) | TOP1SLC2A1 | |
| SCHEMBL26852586 | 0.89 | TOP1 (0.70) | TOP1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381321-A1 | CAMPTOTHECIN CONJUGATES | SEAGEN INC. | 2023-11-30 | — | — | US | disclosed |
| US-20230381321-A1 | CAMPTOTHECIN CONJUGATES | SEAGEN INC. | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381321-A1 | CAMPTOTHECIN CONJUGATES | DCLRE1A, TOP2A, PAICS | TOP1 4/4885SLC2A1 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.