SCHEMBL26294990

SCHEMBL26294990

CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc3c(cc1c2CNCCCN1CCOCC1)OCO3

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 1/20 0.72
▸ TOP1 P11387 19/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26852565 0.96 SLC2A1 (0.74) SLC2A1TOP1
SCHEMBL26852640 0.94 TOP1 (0.72) SLC2A1TOP1
SCHEMBL26852547 0.94 TOP1 (0.81) SLC2A1TOP1
SCHEMBL26276846 0.93 TOP1 (0.70) SLC2A1TOP1
SCHEMBL21450472 0.90 TOP1 (0.79) SLC2A1TOP1
SCHEMBL26852568 0.90 TOP1 (0.73) SLC2A1TOP1
SCHEMBL26275980 0.90 TOP1 (0.83) SLC2A1TOP1
SCHEMBL21590362 0.90 SLC2A1 (0.79) SLC2A1TOP1
SCHEMBL21450468 0.90 TOP1 (0.78) SLC2A1TOP1
SCHEMBL26852560 0.90 TOP1 (0.78) SLC2A1TOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381321-A1 CAMPTOTHECIN CONJUGATES SEAGEN INC. 2023-11-30 — — US disclosed
US-20230381321-A1 CAMPTOTHECIN CONJUGATES SEAGEN INC. 2023-11-30 — — US disclosed
WO-2023178289-A2 CAMPTOTHECIN CONJUGATES SEAGEN INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381321-A1 CAMPTOTHECIN CONJUGATES DCLRE1A, TOP2A, PAICS SLC2A1 3489/4885TOP1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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