SCHEMBL268537

SCHEMBL268537

O=C1NCN(CCO)CN1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 1.00
MAPT P10636 1/20 0.61
GAA P10253 1/20 0.36
MMP2 P08253 4/20 0.33
MMP9 P14780 4/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14159061 0.80
SCHEMBL12534280 0.77
SCHEMBL268470 0.76 KMT2A (0.61) KMT2AMAPTGAAKDM4EALDH1A1
SCHEMBL7563300 0.76 MAPT (1.00) KMT2AMAPTGAAKDM4EALDH1A1
SCHEMBL11743783 0.73 KMT2A (0.57) KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL270149 0.73 KMT2A (0.57) KMT2AGAAALDH1A1LMNAMEN1
SCHEMBL2709587 0.67
SCHEMBL5418820 0.66 KMT2A (0.48) KMT2AMAPTSMN1; SMN2
SCHEMBL17552358 0.65 KMT2A (0.48) KMT2AALDH1A1LMNASMN1; SMN2CYP3A4
SCHEMBL9511613 0.65 KMT2A (0.48) KMT2AMAPTGAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US disclosed
EP-4508111-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME Huntsman Petrochemical LLC (US) 2025-02-19 EP disclosed
CN-117106151-A Composition for reducing the amount of aldehydes discharged from polyurethane foam 亨茨曼石化产品有限责任公司 2023-11-24 CN disclosed
WO-2023200641-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC (US) 2023-10-19 WO disclosed
EP-2760879-B1 PROTEIN-CONTAINING ADHESIVES, AND MANUFACTURE AND USE THEREOF EVERTREE (FR) 2023-06-14 EP disclosed
US-11548997-B2 Method for the reduction of aldehyde emission in polyurethane foam HUNTSMAN INTERNATIONAL LLC (US) 2023-01-10 US disclosed
US-20210395584-A1 PROTEIN-CONTAINING ADHESIVES, AND MANUFACTURE AND USE THEREOF EVERTREE (FR) 2021-12-23 US disclosed
CN-108884206-B Method for reducing aldehyde emissions in polyurethane foams 亨茨曼国际有限公司 2021-08-03 CN disclosed
US-11072731-B2 Protein-containing adhesives, and manufacture and use thereof EVERTREE (FR) 2021-07-27 US disclosed
CN-105026438-B Reduction of aldehydes in amine catalysts 亨斯迈石油化学有限责任公司 2021-07-06 CN disclosed
US-4505712-A Cyclic urea/glyoxal/polyol condensates and their use in treating textile fabrics and paper SUN CHEMICAL CORPORATION (US) 1985-03-19 US disclosed
EP-0132127-A2 Cyclic urea condensates, textile and paper treating compositions and novel cyclic ureas SEQUA CHEMICALS INC. (US) 1985-01-23 EP disclosed
US-4455416-A INSOLUBILIZERS SUN CHEMICAL CORPORATION (US) 1984-06-19 US disclosed
US-4395504-A Adhesive system for particleboard manufacture SUN CHEMICAL CORPORATION (US) 1983-07-26 US disclosed
US-4345063-A Glyoxal/cyclic urea condensates SUN CHEMICAL CORPORATION (US) 1982-08-17 US disclosed
US-4343655-A ALKYLATED GLYOXAL-CYCLIC UREA REACTION PRODUCT SUN CHEMICAL CORPORATION (US) 1982-08-10 US disclosed
US-4332586-A FORMALDEHYDE-FREE SUN CHEMICAL CORPORATION (US) 1982-06-01 US disclosed
US-4300898-A BLENDS OF GLYOXAL/CYCLIC UREA CONDENSATE AND DIMETHYLOL DIHYDROXYETHYLENE UREA FOR WRINKLEPROOFING SUN CHEMICAL CORPORATION (US) 1981-11-17 US disclosed
US-4285690-A ALKYLATED REACTION PRODUCT OF GLYOXAL AND A CYCLIC UREA; FINISHING; FORMALDEHYDE-FREE SUN CHEMICAL CORPORATION (US) 1981-08-25 US disclosed
US-4284758-A CROSSLINKERS FOR TEXTILES SUN CHEMICAL CORP. (US) 1981-08-18 US disclosed