SCHEMBL11743783

SCHEMBL11743783

CN(C)CCN1CNC(=O)NC1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.57
DAO P14920 1/20 0.40
KDM4E B2RXH2 3/20 0.37
DRD2 P14416 1/20 0.34
HTR6 P50406 1/20 0.34
TERT O14746 2/20 0.33
MAPT P10636 1/20 0.33
PIM1 P11309 1/20 0.33
HEXA P06865 1/20 0.33
HEXB P07686 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
SLC6A4 P31645 1/20 0.32
HRH1 P35367 1/20 0.32
MPO P05164 1/20 0.32
HAVCR2 Q8TDQ0 1/20 0.32
PARP1 P09874 1/20 0.32
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10625594 0.78 MAPT (0.57) KMT2ADAOKDM4EMAPTPIM1
SCHEMBL268470 0.77 KMT2A (0.61) KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL270149 0.74 KMT2A (0.57) KMT2A
Hydrochloric Acid SCHEMBL27557995 0.71 PIM1 (0.30) PIM1
SCHEMBL27578379 0.70 PIM1 (0.32) DAOPIM1
SCHEMBL6945820 0.70 KDM4E (0.37) DAOKDM4ETERTMAPTPIM1
SCHEMBL3193395 0.68
SCHEMBL1186740 0.68
SCHEMBL2231151 0.68 PIM1 (0.42) KDM4EMAPTPIM1
SCHEMBL3678345 0.68 ALDH1A1 (0.35) DAOKDM4EMAPTPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4017259-A TERT-AMINO-N-METHYLOL, DURABLE PRESS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-04-12 US disclosed